Modern rheumatology · 2025
A biopsychosocial questionnaire for patients with primary Sjögren's syndrome: The BETY-Biopsychosocial Questionnaire.
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Ahıskalı Gamze Nur, Tüfekçi Orkun, Karaca Nur Banu, Ekici Mustafa, Nacar Nazlı Elif, Buran Sinan, Kantar Mine, Apraş Bilgen Şule, Kiraz Sedat, Ünal Edibe
Аннотация
OBJECTIVE: The BETY-Biopsychosocial Questionnaire (BETY-BQ) is a scale developed to assess the biopsychosocial domains of patients with rheumatic diseases under a single roof. The study aimed to determine the validity and reliability of the BETY-BQ in patients with primary Sjögren's syndrome (pSS).
METHODS: At enrollment and 1 week, 91 patients with pSS completed the BETY-BQ. Construct validity was measured by correlating the BETY-BQ total score responses with the Health Assessment Questionnaire, Hospital Anxiety and Depression Scale, 36-Item Short-Form Health Survey, EULAR Sjögren's Syndrome Patient-Reported Index, EULAR Sjögren's Syndrome Disease Activity Index, Primary Sjögren's Syndrome Quality of Life questionnaire, and Euro-QoL 5D.
RESULTS: The BETY-BQ correlated high to moderate with Health Assessment Questionnaire, bodily pain subscale of 36-Item Short-Form Health Survey, Euro-Qol 5D, Primary Sjögren's Syndrome Quality of Life questionnaire, Hospital Anxiety and Depression Scale, and EULAR Sjögren's Syndrome Patient-Reported Index (0.776 to 0.557, P < .05). Spearman's correlation coefficients between BETY-BQ total scores at baseline and average 1 week were very high (rho = 0.98, P < .001) and indicated substantial agreement between test-retest scores (intraclass correlation coefficient = 0.99, P < .001). Internal consistency reliability at baseline was 0.91 for the BETY-BQ.
CONCLUSIONS: BETY-BQ is valid and reliable for assessing biopsychosocial status in patients with pSS and can be used to measure outcomes in pSS.
METHODS: At enrollment and 1 week, 91 patients with pSS completed the BETY-BQ. Construct validity was measured by correlating the BETY-BQ total score responses with the Health Assessment Questionnaire, Hospital Anxiety and Depression Scale, 36-Item Short-Form Health Survey, EULAR Sjögren's Syndrome Patient-Reported Index, EULAR Sjögren's Syndrome Disease Activity Index, Primary Sjögren's Syndrome Quality of Life questionnaire, and Euro-QoL 5D.
RESULTS: The BETY-BQ correlated high to moderate with Health Assessment Questionnaire, bodily pain subscale of 36-Item Short-Form Health Survey, Euro-Qol 5D, Primary Sjögren's Syndrome Quality of Life questionnaire, Hospital Anxiety and Depression Scale, and EULAR Sjögren's Syndrome Patient-Reported Index (0.776 to 0.557, P < .05). Spearman's correlation coefficients between BETY-BQ total scores at baseline and average 1 week were very high (rho = 0.98, P < .001) and indicated substantial agreement between test-retest scores (intraclass correlation coefficient = 0.99, P < .001). Internal consistency reliability at baseline was 0.91 for the BETY-BQ.
CONCLUSIONS: BETY-BQ is valid and reliable for assessing biopsychosocial status in patients with pSS and can be used to measure outcomes in pSS.