International journal of cardiology · 2024
Predictive value of apical rocking and septal flash for subclinical left ventricular systolic dysfunction in complete left bundle branch block patients with normal left ventricular ejection fraction.
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Chen Mengjia, Pang Bo, Li Guangyuan, Wang Yonghuai, Ma Chunyan
Аннотация
BACKGROUND: This study aimed to evaluate the effects of apical rocking(ApRock) and septal flash(SF) on left ventricular function in complete left bundle branch block(CLBBB) patients with normal left ventricular ejection fraction(LVEF), with the goal of improving risk stratification and clinical decision-making for these patients.
METHODS: Seventy-five CLBBB patients with normal LVEF, and 30 age- and sex-matched controls were enrolled in the study. Three independent physicians visually assessed the presence of ApRock and SF and left ventricular global longitudinal strain(LVGLS) and the standard deviation of time-to-peak strain in 18 segments(Ts-SD) were evaluated using two-dimensional speckle-tracking echocardiography.
RESULTS: CLBBB patients with normal LVEF had significantly decreased LV function and synchrony as evidenced by LVGLS and Ts-SD, and CLBBB patients with either ApRock or SF had lower LVGLS than those without ApRock or SF. LVGLS were further decreased and Ts-SD was further increased in CLBBB patients with both ApRock and SF (P < 0.001). Logistic regression analysis revealed that both ApRock (OR, 4.13; P = 0.04) and SF (OR, 4.12; P = 0.03) were independently associated with LVGLS>-20 %. Combination of ApRock and SF showed the highest area under the curve for identifying LVGLS>-20 %. Furthermore, combination of ApRock and SF improved reclassification compared to ApRock alone.
CONCLUSION: CLBBB patients with normal LVEF showed impaired left ventricular systolic function. The presence of both ApRock and SF was a stronger indicator of subclinical left ventricular impairment compared to either one alone, suggesting that increased attention should be paid to CLBBB patients with normal LVEF, particularly those with both ApRock and SF.
METHODS: Seventy-five CLBBB patients with normal LVEF, and 30 age- and sex-matched controls were enrolled in the study. Three independent physicians visually assessed the presence of ApRock and SF and left ventricular global longitudinal strain(LVGLS) and the standard deviation of time-to-peak strain in 18 segments(Ts-SD) were evaluated using two-dimensional speckle-tracking echocardiography.
RESULTS: CLBBB patients with normal LVEF had significantly decreased LV function and synchrony as evidenced by LVGLS and Ts-SD, and CLBBB patients with either ApRock or SF had lower LVGLS than those without ApRock or SF. LVGLS were further decreased and Ts-SD was further increased in CLBBB patients with both ApRock and SF (P < 0.001). Logistic regression analysis revealed that both ApRock (OR, 4.13; P = 0.04) and SF (OR, 4.12; P = 0.03) were independently associated with LVGLS>-20 %. Combination of ApRock and SF showed the highest area under the curve for identifying LVGLS>-20 %. Furthermore, combination of ApRock and SF improved reclassification compared to ApRock alone.
CONCLUSION: CLBBB patients with normal LVEF showed impaired left ventricular systolic function. The presence of both ApRock and SF was a stronger indicator of subclinical left ventricular impairment compared to either one alone, suggesting that increased attention should be paid to CLBBB patients with normal LVEF, particularly those with both ApRock and SF.