Journal of medical primatology · 2026
Outbreak of Toxoplasmosis Caused by the Brazilian Lineage Type BrII in Black Lion Tamarins (Leontopithecus chrysopygus) Co-Infected With Leishmania sp.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Lima Acauane Sehnem, Dos Santos Daniel Oliveira, Santana Clarissa Helena, de Souza Lucas Dos Reis, da Silva Laice Alves, de Paula Nayara Ferreira, Vieira André Duarte, Tinoco Herlandes Penha, Coelho Carlyle Mendes, de Oliveira Ayisa Rodrigues, Pena Hilda Fátima Jesus, Santos Renato Lima
Аннотация
BACKGROUND: Toxoplasmosis and leishmaniosis are zoonotic diseases that affect several species of neotropical primates.
METHODS: Three black lion tamarins (Leontopithecus chrysopygus) kept at a Brazilian zoo died due to a superacute disease. Tissue samples were collected for histopathology, cytology, PCR, and genotyping by PCR-RFLP and microsatellite (MS) analysis.
RESULTS: Toxoplasma gondii was detected by PCR in all tissue samples analyzed. The Brazilian lineage Type BrII (ToxoDB-PCR-RFLP #11 genotype) was identified in three animals, and the analysis with MS confirmed the same source of infection. Amastigotes of Leishmania sp. were visualized in cytology and confirmed by IHC in the three animals.
CONCLUSION: This is the first time that this genotype has been confirmed associated with an outbreak of toxoplasmosis affecting neotropical primates in Brazil, or associated with infection by Leishmania sp.
METHODS: Three black lion tamarins (Leontopithecus chrysopygus) kept at a Brazilian zoo died due to a superacute disease. Tissue samples were collected for histopathology, cytology, PCR, and genotyping by PCR-RFLP and microsatellite (MS) analysis.
RESULTS: Toxoplasma gondii was detected by PCR in all tissue samples analyzed. The Brazilian lineage Type BrII (ToxoDB-PCR-RFLP #11 genotype) was identified in three animals, and the analysis with MS confirmed the same source of infection. Amastigotes of Leishmania sp. were visualized in cytology and confirmed by IHC in the three animals.
CONCLUSION: This is the first time that this genotype has been confirmed associated with an outbreak of toxoplasmosis affecting neotropical primates in Brazil, or associated with infection by Leishmania sp.