Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology · 2013
[Serum interleukin-18 level in precancerous conditions and gastric cancer].
Аннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Matveeva L V, Mosina L M
Аннотация
UNLABELLED: The purpose of the study--to determine the serum concentration and the pathogenetic significance of changes of interleukin-18 in patients with chronic atrophic gastritis, peptic ulcer disease and gastric cancer. MATERIAL AND METHODS.:A comprehensive survey of 192 patients with diseases gastroduodenal zone. Diagnostic emphasis was placed on ELISA method as defined in the serum of IL-18, --1beta, interferon-gamma, kantsernogo antigen 19-9, vascular endothelial growth factor, total antibodies to CagA Helicobacter pylori.
RESULTS: We examined patients revealed an increase in the concentration of interleukin-18, which correlated with tumor stage, the level of vascular endothelial growth factor, total antibodies to CagA Helicobacter pylori.
CONCLUSION: The data obtained allow to recommend the use of interleukin-18 in serum for diagnostic of atrophic gastritis, peptic ulcer diseases and gastric cancer.
RESULTS: We examined patients revealed an increase in the concentration of interleukin-18, which correlated with tumor stage, the level of vascular endothelial growth factor, total antibodies to CagA Helicobacter pylori.
CONCLUSION: The data obtained allow to recommend the use of interleukin-18 in serum for diagnostic of atrophic gastritis, peptic ulcer diseases and gastric cancer.