Journal of gastroenterology and hepatology · 2008
Normalization of pH level and gastric mucosa after eradication of H. pylori in the remnant stomach.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Kato Shunji, Matsukura Norio, Matsuda Noriko, Tsuchiya Shinichi, Naito Zenya, Tajiri Takashi
Аннотация
BACKGROUND: The Updated Sydney System (USS) is used to evaluate chronic gastritis and chronic atrophic gastritis (CAG) due to H. pylori infection. Here, we investigated USS scores and gastric juice pH levels in H. pylori infection-positive or -eradicated patients with remnant stomach after surgery.
METHODS: Gastric juice pH levels were measured using pH test-tape in 197 patients (112 H. pylori-positive and 85 H. pylori-negative after eradication) who had undergone distal gastrectomy and conventional H. pylori eradication therapy.
RESULTS: In H. pylori infection-positive remnant stomach cases, gastric juice pH showed a reverse correlation with pepsinogen I/II ratio, and H. pylori infection-negative patients following eradication showed associations with the degree of atrophy and intestinal metaplasia at both the anastomosis and in the corpus. Further, pH levels in these patients were normalized time depending after the eradication in the remnant stomach.
CONCLUSIONS: Eradication therapy for the remnant stomach contributes to the possible improvement of stomach conditions by controlling the pH level of gastric juice. This effect will be protective against the risk of secondary stomach carcinogenesis in the remnant stomach.
METHODS: Gastric juice pH levels were measured using pH test-tape in 197 patients (112 H. pylori-positive and 85 H. pylori-negative after eradication) who had undergone distal gastrectomy and conventional H. pylori eradication therapy.
RESULTS: In H. pylori infection-positive remnant stomach cases, gastric juice pH showed a reverse correlation with pepsinogen I/II ratio, and H. pylori infection-negative patients following eradication showed associations with the degree of atrophy and intestinal metaplasia at both the anastomosis and in the corpus. Further, pH levels in these patients were normalized time depending after the eradication in the remnant stomach.
CONCLUSIONS: Eradication therapy for the remnant stomach contributes to the possible improvement of stomach conditions by controlling the pH level of gastric juice. This effect will be protective against the risk of secondary stomach carcinogenesis in the remnant stomach.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAnti-Bacterial AgentsBiopsyChronic DiseaseFemaleGastrectomyGastric AcidGastric Acidity DeterminationGastric MucosaGastric StumpGastritis, AtrophicGastroscopyHelicobacter InfectionsHelicobacter pyloriHumansHydrogen-Ion ConcentrationMaleMiddle AgedPepsinogen APepsinogen CSeverity of Illness IndexStomach NeoplasmsTreatment Outcome