Head & neck · 2010
Changes in nutritional status and dietary intake during and after head and neck cancer treatment.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Jager-Wittenaar Harriët, Dijkstra Pieter U, Vissink Arjan, Langendijk Johannes A, van der Laan Bernard F A M, Pruim Jan, Roodenburg Jan L N
Аннотация
BACKGROUND: The purpose of this study was to test whether nutritional status of patients with head and neck cancer changes during and after treatment.
METHODS: Nutritional status (including body weight, lean mass, and fat mass) and dietary intake were assessed in 29 patients with head and neck cancer. Patients were assessed 1 week before, and 1 and 4 months after treatment (radiotherapy, either alone or combined with chemotherapy or surgery).
RESULTS: During treatment, body weight (-3.6 ± 5.3 kg; p = .019) and lean mass (-2.43 ± 2.81 kg; p = .001) significantly declined. Patients with sufficient intake (≥35 kcal and ≥1.5 grams protein/kg body weight) lost less body weight and lean mass than patients with insufficient intake (mean difference, -4.0 ± 1.9 kg; p = 0.048 and -2.1 ± 1.0 kg; p = .054, respectively). After treatment, only patients with sufficient intake gained body weight (2.3 ± 2.3 kg) and lean mass (1.2 ± 1.3 kg).
CONCLUSION: Patients with head and neck cancer fail to maintain or improve nutritional status during treatment, despite sufficient intake.
METHODS: Nutritional status (including body weight, lean mass, and fat mass) and dietary intake were assessed in 29 patients with head and neck cancer. Patients were assessed 1 week before, and 1 and 4 months after treatment (radiotherapy, either alone or combined with chemotherapy or surgery).
RESULTS: During treatment, body weight (-3.6 ± 5.3 kg; p = .019) and lean mass (-2.43 ± 2.81 kg; p = .001) significantly declined. Patients with sufficient intake (≥35 kcal and ≥1.5 grams protein/kg body weight) lost less body weight and lean mass than patients with insufficient intake (mean difference, -4.0 ± 1.9 kg; p = 0.048 and -2.1 ± 1.0 kg; p = .054, respectively). After treatment, only patients with sufficient intake gained body weight (2.3 ± 2.3 kg) and lean mass (1.2 ± 1.3 kg).
CONCLUSION: Patients with head and neck cancer fail to maintain or improve nutritional status during treatment, despite sufficient intake.
Предметные рубрики MeSH
AgedAnalysis of VarianceBody CompositionBody Mass IndexCohort StudiesCombined Modality TherapyDietary ProteinsEnergy IntakeFemaleFollow-Up StudiesHead and Neck NeoplasmsHumansLinear ModelsMaleMalnutritionMiddle AgedMonitoring, PhysiologicNutritional RequirementsNutritional StatusPostoperative CareProspective StudiesRisk AssessmentStatistics, NonparametricTime FactorsWeight Loss