Methylphenidate for medical in-patients.

Methylphenidate (Ritalin Hydrochloride) has been recommended as a treatment for depressed medical and geriatric patients. The rationale for this treatment includes both its safety (even in patients with contra-indications that prevent the use of other antidepressants) and its quick onset of action. In addition the drug can be withdrawn after a few weeks of treatment without the danger of a recurrence of depression. The author reports having used the drug safety in depressed medically ill patients with a success rate of at least 50 percent.