Journal of assisted reproduction and genetics · 2025
"How did it go?"-investigation of physician's experience during embryo transfer and subsequent pregnancy outcomes.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Pierpoint Sara C, Peavey Mary, Goodman Linnea
Аннотация
PURPOSE: This research sought to investigate if a physician's experience of an embryo transfer (ET) correlates to rates of success.
METHODS: A single experienced physician rated characteristics of ETs including ease of transfer (1-10), visibility (1-10), presence of blood, and amount of mucus (0-3) at the time of ET. Main outcomes were positive beta-human chorionic gonadotropin level 11 days post transfer and ongoing pregnancy rate.
RESULTS: A total of 365 transfers were rated. The average age of patients was 34.2 + / - 4.6 years. A total of 69.6% of cycles were programmed, and 73.2% of the transferred embryos underwent pre-implantation genetic testing for aneuploidy (PGT-a) prior to transfer. Average ease of transfer scores (9.3 + / - 1.7 vs 9.2 + / - 1.7; p = 0.71) and visibility scores (8.3 + / - 2.3 vs 8.1 + / - 2.8; p = 0.37) were similar between positive and negative pregnancy tests, respectively. Blood and mucus did not influence pregnancy rates. There was no correlation between ease of mock and actual embryo transfers. Multivariate logistic regression for positive bHCG demonstrated a significant predictive value for PGT-a (OR 2.50, 95% CI 1.47-4.23). Ease of transfer (OR 1.02, 95% CI 0.88-1.15), visibility (OR 1.04, 95% CI 0.94-1.15), mucus (OR 1.00, 95% CI 0.77-1.30), and embryo age (OR 0.98, 95% CI 0.92-1.03) were not predictive.
CONCLUSIONS: In experienced hands, physician subjective impressions of transfer characteristics were not significantly correlated with a successful transfer.
METHODS: A single experienced physician rated characteristics of ETs including ease of transfer (1-10), visibility (1-10), presence of blood, and amount of mucus (0-3) at the time of ET. Main outcomes were positive beta-human chorionic gonadotropin level 11 days post transfer and ongoing pregnancy rate.
RESULTS: A total of 365 transfers were rated. The average age of patients was 34.2 + / - 4.6 years. A total of 69.6% of cycles were programmed, and 73.2% of the transferred embryos underwent pre-implantation genetic testing for aneuploidy (PGT-a) prior to transfer. Average ease of transfer scores (9.3 + / - 1.7 vs 9.2 + / - 1.7; p = 0.71) and visibility scores (8.3 + / - 2.3 vs 8.1 + / - 2.8; p = 0.37) were similar between positive and negative pregnancy tests, respectively. Blood and mucus did not influence pregnancy rates. There was no correlation between ease of mock and actual embryo transfers. Multivariate logistic regression for positive bHCG demonstrated a significant predictive value for PGT-a (OR 2.50, 95% CI 1.47-4.23). Ease of transfer (OR 1.02, 95% CI 0.88-1.15), visibility (OR 1.04, 95% CI 0.94-1.15), mucus (OR 1.00, 95% CI 0.77-1.30), and embryo age (OR 0.98, 95% CI 0.92-1.03) were not predictive.
CONCLUSIONS: In experienced hands, physician subjective impressions of transfer characteristics were not significantly correlated with a successful transfer.