Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2015
Platelet-rich plasma for resistant oral erosions of pemphigus vulgaris: A pilot study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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EL-Komy Mohamed Hussein Medhat, Hassan Akmal Saad, Abdel Raheem Heba Mohammed, Doss Sally Sameh, EL-Kaliouby Mona, Saleh Noha Adly, Saleh Marwah Adly
Аннотация
Oral erosions and ulcers of pemphigus vulgaris (PV) are a debilitating condition that is usually difficult to treat. The wound healing properties of platelet-rich plasma (PRP) encouraged us to evaluate its usefulness in treatment of non-healing oral PV lesions. Seven patients with chronic oral PV, resistant to conventional therapy, were treated with weekly to monthly injections of PRP of affected mucosal membranes. All recruits reported improvement in pain and mastication and 6 of 7 patients had an improvement in pemphigus disease area index scores with PRP treatment. PRP injections seems to accelerate the healing process and decrease the pain and eating discomfort associated with the oral erosions and ulcers induced by PV.