Photodiagnosis and photodynamic therapy · 2025
The corneal biomechanics of the posterior staphyloma.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Liao Xiqiong, Yu Guanshun, Jiang Yi, Zhuang Xiaoyu, Yao Shumeng, Li Kaige, Yu Shuhan, Wang Yi, Liang Yuanbo, Dai Qi, Fu Lin
Аннотация
PURPOSE: To compare the corneal biomechanical differences of eyes with and without posterior staphyloma (PS) using Corneal Visualization Scheimpflug Technology (Corvis ST).
METHODS: This is a cross-sectional study. The patients were classified into the PS group and control group. Corneal biomechanical parameters were measured by Corvis ST and compared between the two groups and among different PS subtypes.
RESULTS: This study included 40 patients in the PS group and the control group respectively. The deformation amplitude at the highest concavity (HCDA), deflection amplitude at the highest concavity, max deflection amplitude (DLA max) and deformation amplitude ratio max at 2 mm were significant higher in the PS group after adjusting the axial length (AL). After matching the AL, only the HCDA and DLA max were significantly greater in the PS group. There was no significant difference in corneal biomechanical parameters among the subtype PS. The A2 V, PD, Radius, HCDA, HCDLL, HCDLA, A2DLA, DLAmax, HC dArc Length, A2 dArc Length, dArc Length Max, DA Ratio Max, Integrated Radius are significantly correlated with PS. In distinguishing PS, DLA Max achieved the highest diagnostic performance, with an area under the receiver operating characteristic curve (AUROC) of 0.79 (95 % CI,0.71-0.85), meanwhile, the area under the ROC curve of all data after the combination of gender and age was 0.813(95 %CI:0.74-0.88).
CONCLUSION: Eyes with posterior staphyloma (PS) exhibit greater corneal deformability, elasticity, and viscoelasticity than controls, independent of PS location. These findings suggest PS impacts the anterior ocular wall, offering insights into PS pathogenesis.
METHODS: This is a cross-sectional study. The patients were classified into the PS group and control group. Corneal biomechanical parameters were measured by Corvis ST and compared between the two groups and among different PS subtypes.
RESULTS: This study included 40 patients in the PS group and the control group respectively. The deformation amplitude at the highest concavity (HCDA), deflection amplitude at the highest concavity, max deflection amplitude (DLA max) and deformation amplitude ratio max at 2 mm were significant higher in the PS group after adjusting the axial length (AL). After matching the AL, only the HCDA and DLA max were significantly greater in the PS group. There was no significant difference in corneal biomechanical parameters among the subtype PS. The A2 V, PD, Radius, HCDA, HCDLL, HCDLA, A2DLA, DLAmax, HC dArc Length, A2 dArc Length, dArc Length Max, DA Ratio Max, Integrated Radius are significantly correlated with PS. In distinguishing PS, DLA Max achieved the highest diagnostic performance, with an area under the receiver operating characteristic curve (AUROC) of 0.79 (95 % CI,0.71-0.85), meanwhile, the area under the ROC curve of all data after the combination of gender and age was 0.813(95 %CI:0.74-0.88).
CONCLUSION: Eyes with posterior staphyloma (PS) exhibit greater corneal deformability, elasticity, and viscoelasticity than controls, independent of PS location. These findings suggest PS impacts the anterior ocular wall, offering insights into PS pathogenesis.