Academic radiology · 2026
Development of a Scoring System For Severe Acute Pancreatitis And Utility of US-guided Catheter Drainage in High-risk Patients.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Long Haiyi, Lin Jielan, Zheng Ruiying, Sun Yueting, Zhou Wenying, Liu Baoxian, Xu Ming, Xie Xiaoyan, Huang Guangliang
Аннотация
RATIONALE AND OBJECTIVES: Severe acute pancreatitis (SAP) carries a high mortality rate. This study aimed to develop a rapid scoring system using admission laboratory parameters to predict mortality in SAP and to evaluate whether high-risk patients identified by this score benefit from ultrasound-guided percutaneous catheter drainage (PCD).
MATERIALS AND METHODS: In this retrospective study, 469 SAP patients (304 conservative, 165 PCD) from January 2015 to March 2023 were included. After propensity score matching for age, sex, and etiology, 316 well-balanced patients (158 per group) were analyzed. A scoring system was developed from the conservative cohort using multivariate logistic regression, with mortality as the primary outcome.
RESULTS: A scoring system was created comprising procalcitonin >1.195 ng/ml (1 point), RBC <3.61×10¹²/L (1 point), WBC >20.2×10⁹/L (2 points), and platelet <149×10⁹/L (1 point). A cutoff of ≥3 points predicted mortality with an AUC of 0.965. Among high-risk patients (score≥3), mortality was significantly lower in the PCD group than in the conservative group (20.6% vs. 57.1%, p=0.006). Furthermore, PCD performed within two weeks of onset was associated with lower mortality than later intervention (9.5% vs. 22.2%, p=0.026).
CONCLUSION: The proposed scoring system effectively identifies high-risk SAP patients who may obtain a substantial survival benefit from early PCD intervention.
MATERIALS AND METHODS: In this retrospective study, 469 SAP patients (304 conservative, 165 PCD) from January 2015 to March 2023 were included. After propensity score matching for age, sex, and etiology, 316 well-balanced patients (158 per group) were analyzed. A scoring system was developed from the conservative cohort using multivariate logistic regression, with mortality as the primary outcome.
RESULTS: A scoring system was created comprising procalcitonin >1.195 ng/ml (1 point), RBC <3.61×10¹²/L (1 point), WBC >20.2×10⁹/L (2 points), and platelet <149×10⁹/L (1 point). A cutoff of ≥3 points predicted mortality with an AUC of 0.965. Among high-risk patients (score≥3), mortality was significantly lower in the PCD group than in the conservative group (20.6% vs. 57.1%, p=0.006). Furthermore, PCD performed within two weeks of onset was associated with lower mortality than later intervention (9.5% vs. 22.2%, p=0.026).
CONCLUSION: The proposed scoring system effectively identifies high-risk SAP patients who may obtain a substantial survival benefit from early PCD intervention.