New-Onset Salt-and-Pepper Skin Changes Associated With Vaccination and Trauma in Systemic Sclerosis: Immunity Matters.

In the recent issue ofThe Journal of Rheumatology, Chung et al1 reported the associations of perifollicular hypopigmentation with disease subtypes and organ involvement in a systemic sclerosis (SSc) cohort in the United States. Perifollicular hypopigmentation, also termed salt-and-pepper appearance, is a typical manifestation in SSc.