Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2025
Time in Range Is Closely Related to Healing Time of Diabetic Foot Ulcers.
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Ortiz-Zúñiga Ángel M, Simó-Servat Olga, Samaniego Jordi, Cuadra-Espinilla Fátima, Sánchez Mónica, Simó Rafael, Hernández Cristina
Аннотация
Diabetic foot ulcer is a meaningful risk factor for limb amputation. The aim of this study was to evaluate the relationship between parameters provided by Continuous Glucose Monitoring and the healing time of DFUs in the real world. This pilot prospective study included patients with Type 2 diabetes with DFUs grade I-II (stage A-C) of the University of Texas Diabetic Wound Classification System, treated in an outpatient Diabetic Foot Unit according to standards of care. Participants were fitted with a CGM device until the ulcer closure. We observed an inverse correlation between the elapsed time to achieve a complete ulcer closure and Time in Range (p = 0.005). In addition, a direct correlation was found between the time required for ulcer healing and both Time Above Range and Glucose Management Indicator (p < 0.05). Glycaemic control is directly related to ulcer wound healing in non-complicated diabetic foot ulcer.