Plasmodium and Host Immunity: Evasion Strategies and Advances in Malaria Vaccination.

Malaria is an infectious disease caused by parasites of the Plasmodium genus. Its pathophysiology is highly complex, as it depends both on the host's immune response and the parasite's evasion mechanisms, which are often species-specific. This complexity has posed significant challenges to vaccine development and malaria control. Therefore, the aim of this review is to describe the host's immunological mechanisms, the parasite's evasion strategies and the available vaccines, as well as their relationship with the human immune response in controlling Plasmodium infection.