The British journal of dermatology · 1982
Circulating testosterone, sex hormone binding globulin and prolactin in women with late onset or persistent acne vulgaris.
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Darley C R, Kirby J D, Besser G M, Munro D D, Edwards C R, Rees L H
Аннотация
Serum testosterone, sex hormone binding globulin (SHBG) and prolactin were measured in thirty-eight women with acne which persisted or started after the age of 18 years. One or more of these levels were abnormal in 76% of patients. Increased testosterone or low SHBG were present alone or in combination in 60% of patients. This group was presumed to have a raised level of non-protein bound, metabolically-available testosterone. Hyperprolactinaemia, which was present in 45% of patients, may be important in view of the reported association with increased adrenal androgens. The hormonal abnormalities may be causally related to the acne and a greater understanding of them may lead to better treatment.