Penicillamine-induced pemphigus foliaceus. A fatal outcome.

Penicillamine-induced pemphigus is an uncommon but well-recognized phenomenon. It has been generally believed to be a benign disease responding to withdrawal of the drug or to treatment with a short course of oral steroids. In the hope that it will increase awareness of the potential severity of this disease, we report herein a case of penicillamine-induced pemphigus foliaceus with fatal termination.