Chronic Staphylococcus aureus infection leading to pyogenic granuloma and preventing socket re-epithelialization after orbital exenteration.

A 71-year-old woman underwent extenteration for conjunctival melanoma with orbital invasion. Her socket failed to epithelialize and contained a diffuse pyogenic granuloma that was caused by chronic Staphylococcus aureus infection. Extensive debridement and long-term intravenous antibiotics resulted in normal healing.