The British journal of ophthalmology · 2007
Influence of ageing on visual field defects due to stable lesions.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rudolph Thiemo, Frisén Lars
Аннотация
BACKGROUND: Knowledge about the effects of ageing on visual field defects is very sparse.
METHODS: Long-term follow-up records were examined from 28 patients with light-to-moderate visual field defects remaining after surgery for pituitary tumours. All were proven free from tumour recurrences and complicating disorders. Hence, all had isolated, stable lesions of the chiasm. Follow-up periods ranged over 4-18 years (median 9). Using high-pass resolution perimetry, results were analysed from the central-most test locations in the upper temporal and upper nasal quadrants. The former typically bear the brunt of damage whereas the latter are least affected. Each patient contributed results from one eye only. Fixation stability and reproducibility were uniformly good.
RESULTS: Measuring values from the nasal quadrants remained essentially constant throughout the follow-up periods. Results from the temporal (T) quadrants were contrasted with those from the nasal (N) quadrants by calculating the T/N ratios, which were then individually regressed over follow-up periods. Hence, each patient was his or her own control. The absolute majority of regression coefficients (25 out of 28) did not significantly differ from 0.
CONCLUSION: The rate of age-related loss of neural channels appears to be identical in normal and abnormal visual field areas in subjects with stable mid-chiasmal lesions.
METHODS: Long-term follow-up records were examined from 28 patients with light-to-moderate visual field defects remaining after surgery for pituitary tumours. All were proven free from tumour recurrences and complicating disorders. Hence, all had isolated, stable lesions of the chiasm. Follow-up periods ranged over 4-18 years (median 9). Using high-pass resolution perimetry, results were analysed from the central-most test locations in the upper temporal and upper nasal quadrants. The former typically bear the brunt of damage whereas the latter are least affected. Each patient contributed results from one eye only. Fixation stability and reproducibility were uniformly good.
RESULTS: Measuring values from the nasal quadrants remained essentially constant throughout the follow-up periods. Results from the temporal (T) quadrants were contrasted with those from the nasal (N) quadrants by calculating the T/N ratios, which were then individually regressed over follow-up periods. Hence, each patient was his or her own control. The absolute majority of regression coefficients (25 out of 28) did not significantly differ from 0.
CONCLUSION: The rate of age-related loss of neural channels appears to be identical in normal and abnormal visual field areas in subjects with stable mid-chiasmal lesions.