Archives of otolaryngology--head & neck surgery · 1995
Metastatic melanoma to the cerebellopontine angle. Clinical and imaging characteristics.
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Arriaga M A, Lo W W, Brackmann D E
Аннотация
OBJECTIVE: To describe the clinical and imaging features of metastatic melanoma to the cerebellopontine angle (CPA).
DESIGN: A case series study with world literature review.
SETTING: House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif.
PATIENTS: Three cases of metastatic CPA tumors operated on at the House Ear Clinic.
INTERVENTIONS: All patients underwent surgical removal of CPA metastatic melanoma.
MAIN OUTCOME MEASURE: Survival and duration of disease-free interval are reported.
RESULTS: Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform.
CONCLUSIONS: Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the long-term prognosis for patients with CPA melanoma is grim.
DESIGN: A case series study with world literature review.
SETTING: House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif.
PATIENTS: Three cases of metastatic CPA tumors operated on at the House Ear Clinic.
INTERVENTIONS: All patients underwent surgical removal of CPA metastatic melanoma.
MAIN OUTCOME MEASURE: Survival and duration of disease-free interval are reported.
RESULTS: Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform.
CONCLUSIONS: Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the long-term prognosis for patients with CPA melanoma is grim.