Paroxetine-associated spontaneous sexual stimulation.

The sexual side-effects of selective serotonin reuptake inhibitors have been widely accepted and clinicians should only prescribe these agents for the treatment of premature ejaculation in the real clinical practice. We recently experienced three cases of paroxetine-associated sexual stimulation in the outpatient clinic. Because there is little information in the existing literature on this issue, we report three female cases who developed frequent spontaneous orgasm and increased libido during paroxetine treatment.