MedElevator Войти в исследования
← Поиск публикаций

DOI 10.5301/ijao.5000482

Медицинская библиотека · The International journal of artificial organs · 2016

A two-stage rotary blood pump design with potentially lower blood trauma: a computational study.

Thamsen Bente, Mevert Ricardo, Lommel Michael, Preikschat Philip, Gaebler Julia, Krabatsch Thomas, Kertzscher Ulrich, Hennig Ewald, Affeld Klaus

СтатьяПеревод пока не подготовлен

Аннотация

AIM: In current rotary blood pumps, complications related to blood trauma due to shear stresses are still frequently observed clinically. Reducing the rotor tip speed might decrease blood trauma. Therefore, the aim of this project was to design a two-stage rotary blood pump leading to lower shear stresses.

METHODS

Using the principles of centrifugal pumps, two diagonal rotor stages were designed with an outer diameter of 22 mm. The first stage begins with a flow straightener and terminates with a diffusor, while a volute casing behind the second stage is utilized to guide fluid to the outlet. Both stages are combined into one rotating part which is pivoted by cup-socket ruby bearings. Details of the flow field were analyzed employing computational fluid dynamics (CFD). A functional model of the pump was fabricated and the pressure-flow dependency was experimentally assessed.

RESULTS

Measured pressure-flow performance of the developed pump indicated its ability to generate adequate pressure heads and flows with characteristic curves similar to centrifugal pumps. According to the CFD results, a pressure of 70 mmHg was produced at a flow rate of 5 L/min and a rotational speed of 3200 rpm. Circumferential velocities could be reduced to 3.7 m/s as compared to 6.2 m/s in a clinically used axial rotary blood pump. Flow fields were smooth with well-distributed pressure fields and comparatively few recirculation or vortices. Substantially smaller volumes were exposed to high shear stresses >150 Pa.

CONCLUSIONS

Hence, blood trauma might be reduced with this design. Based on these encouraging results, future in vitro investigations to investigate actual blood damage are intended.

Для цитирования: Thamsen Bente, Mevert Ricardo, Lommel Michael, Preikschat Philip, Gaebler Julia, Krabatsch Thomas, Kertzscher Ulrich, Hennig Ewald, Affeld Klaus. A two-stage rotary blood pump design with potentially lower blood trauma: a computational study.. The International journal of artificial organs. 2016. DOI: 10.5301/ijao.5000482.

Предметные рубрики MeSH

Подготовка и перевод публикации
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Тип публикации указан по данным источника. Уровень доказательности автоматически не присваивается.