[Interpretation of key updates in the "Consensus on the diagnosis and treatment of pituitary prolactinoma (2025 edition)"].

The "Consensus on the diagnosis and treatment of pituitary prolactinoma (2025 edition)" is based on the latest evidence-based medicine evidence and has comprehensively refined the diagnosis and treatment strategies for prolactinoma. In terms of diagnosis, the consensus optimizes the imaging evaluation process and introduces innovative recommendations such as aneurysm screening. In terms of treatment, the consensus clarifies a step-by-step medication strategy, establishes the important position of neuroendoscopic surgery for well-defined adenomas with Knosp 0-1 grade, and refines the application details of radiotherapy. In terms of the management of special populations, the consensus significantly strengthens the refined and individualized management plans for refractory prolactinoma, male patients, pregnant patients, etc. The artical vertically compars the evolution of the 2025 edition consensus with the 2014 edition consensus, horizontally compars its similarities and differences with international consensus, and deeply explores the clinical value and current limitations of the new edition consensus, in order to provide references for clinical practice and jointly promote the improvement of the diagnosis and treatment level of prolactinoma in China.