Internal medicine (Tokyo, Japan) · 2015
Association of Primary Biliary Cirrhosis-autoimmune Hepatitis Overlap Syndrome with Immune Thrombocytopenia and Graves' Disease.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Koyamada Ryosuke, Higuchi Takakazu, Kitada Ayako, Nakagawa Tomoko, Ikeya Takashi, Okada Sadamu, Fujita Yoshiyuki
Аннотация
A 54-year-old woman suffering from pruritus for five years was diagnosed to have Graves' disease and immune thrombocytopenia (ITP) associated with primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome, which was confirmed histologically after a prompt recovery in the platelet count number following steroid therapy. The association between PBC-AIH overlap syndrome and ITP has been rarely reported and the additional association with Graves' disease has not yet been reported. An underlying global derangement of autoimmunity or shared genetic susceptibility was suspected.