Disability and rehabilitation · 2025
Physical exercise and breast cancer-related lymphedema: an umbrella review, systematic review and meta-analysis.
СтатьяСистематический обзорМетаанализНазвание и аннотация: Перевод пока не подготовлен
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García-Chico Celia, López-Ortiz Susana, Pinto-Fraga José, Ceci Claudia, Valenzuela Pedro L, Peñín-Grandes Saúl, Maroto-Izquierdo Sergio, Graziani Grazia, Fiuza-Luces Carmen, Lista Simone, Lucia Alejandro, Santos-Lozano Alejandro
Аннотация
PURPOSE: The present study aimed to summarize the current evidence on the impact of exercise in patients at risk or with breast cancer-related lymphedema (BCRL) through an umbrella review of existing meta-analysis and a systematic review and meta-analysis of randomized controlled trials (RCTs).
MATERIAL AND METHODS: A search was conducted in PubMed and Web of Science up to June 2025 to identify meta-analyses and RCTs that included exercise interventions in patients at risk or with BCRL.
RESULTS: Three systematic reviews including 14 individual meta-analyses were included in the umbrella review. Two of these met the criteria of strong evidence, reporting beneficial effects of exercise on upper- and lower-body strength. A total of 46 RCTs were included in the systematic review, of which 11 could be meta-analyzed. Strong evidence was found for a beneficial effect of exercise on upper- and lower-body strength and upper-limb disability.
CONCLUSION: Strong evidence supports the beneficial effects of exercise on upper- and lower-body strength and upper-limb disability in patients at risk or with BCRL.
MATERIAL AND METHODS: A search was conducted in PubMed and Web of Science up to June 2025 to identify meta-analyses and RCTs that included exercise interventions in patients at risk or with BCRL.
RESULTS: Three systematic reviews including 14 individual meta-analyses were included in the umbrella review. Two of these met the criteria of strong evidence, reporting beneficial effects of exercise on upper- and lower-body strength. A total of 46 RCTs were included in the systematic review, of which 11 could be meta-analyzed. Strong evidence was found for a beneficial effect of exercise on upper- and lower-body strength and upper-limb disability.
CONCLUSION: Strong evidence supports the beneficial effects of exercise on upper- and lower-body strength and upper-limb disability in patients at risk or with BCRL.