Effectiveness of an Integrated One Health Intervention on Schistosoma japonicum Infection in Wild Rodents - Anhui Province, China, 2022-2024.

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Schistosomiasis represents a natural focal disease in which wild rodents function as critical reservoir hosts for Schistosoma japonicum transmission within specific endemic regions of China.

WHAT IS ADDED BY THIS REPORT?: Implementation of a comprehensive 2-year One Health intervention package demonstrated a significant reduction in S. japonicum infection rates among wild rodents, declining from 69.15% to 22.09%, with intervention villages showing an 88.46% decrease in infection odds compared to control villages.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Integrating One Health intervention measures into schistosomiasis control programs could effectively reduce infection risk among environmental reservoir hosts and mitigate transmission risks to human populations.