Regenerative therapy · 2025
The effect of l-lactide-ε-caprolactone copolymer membrane on alveolar bone preservation: A comparative study using the open healing approach.
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Takabayashi Masayuki, Yahata Yoshio, Handa Keisuke, Kyaw Moe Sandar, Suresh Venkata Venkataih, Saito Masahiro
Аннотация
INTRODUCTION: This study evaluated the efficacy of a resorbable l-lactide-ε-caprolactone copolymer (PLCL) membrane in promoting epithelial healing and preserving alveolar bone morphology using the open healing approach (OHA), compared to conventional membranes.
METHODS: Extraction sockets in beagle dogs were filled with bone substitute material and covered with different membranes. Healing was assessed via histological analysis and micro-CT imaging.
RESULTS: The PLCL membrane reduced bone resorption and preserved alveolar bone morphology better than conventional membranes. Histological analysis showed excellent epithelial healing and notable bone formation.
CONCLUSIONS: The PLCL membrane effectively prevents infection, supports epithelial healing, and preserves alveolar bone morphology in OHA procedures.
METHODS: Extraction sockets in beagle dogs were filled with bone substitute material and covered with different membranes. Healing was assessed via histological analysis and micro-CT imaging.
RESULTS: The PLCL membrane reduced bone resorption and preserved alveolar bone morphology better than conventional membranes. Histological analysis showed excellent epithelial healing and notable bone formation.
CONCLUSIONS: The PLCL membrane effectively prevents infection, supports epithelial healing, and preserves alveolar bone morphology in OHA procedures.