Journal of acquired immune deficiency syndromes (1999) · 2025
Entering HIV Medical Care With AIDS in the Era of Immediate Access to Antiretroviral Treatment.
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Rodriguez Allan E, Botero Valeria, Geffrard Anjalie, Saltzman Russell G, Alvarez Victoria, Kolber Michael A
Аннотация
BACKGROUND: Despite advancements in rapid HIV care access, a significant portion of people living with HIV still enter care with advanced disease (AIDS). Test and Treat/Rapid Access (TTRA) programs focused on rapid detection and treatment are widespread in the United States. However, a significant proportion of patients enter care through the traditional standard of care where, after a case manager evaluation, an initial appointment is generated for an HIV provider, a process that could take 2-4 weeks.
OBJECTIVES: This study conducted at the University of Miami/Jackson Memorial Hospital Adult HIV Outpatient Clinic-the largest single-site clinic in Miami Dade, a central hub of the HIV epidemic-analyzes individuals who enrolled during the initial 2 years of our TTRA program.
METHODS: We compared the clinical outcomes of patients diagnosed with AIDS entering through the TTRA versus those using the standard of care.
RESULTS: Our findings indicate substantial improvements in HIV viral loads and CD4 counts for both groups. However, patients entering through standard of care, who were more likely to have had prior hospitalizations because of opportunistic infections, tended to be older and predominantly contracted HIV through heterosexual transmission. In contrast, those entering TTRA experienced quicker virologic suppression and superior immunologic recovery.
OBJECTIVES: This study conducted at the University of Miami/Jackson Memorial Hospital Adult HIV Outpatient Clinic-the largest single-site clinic in Miami Dade, a central hub of the HIV epidemic-analyzes individuals who enrolled during the initial 2 years of our TTRA program.
METHODS: We compared the clinical outcomes of patients diagnosed with AIDS entering through the TTRA versus those using the standard of care.
RESULTS: Our findings indicate substantial improvements in HIV viral loads and CD4 counts for both groups. However, patients entering through standard of care, who were more likely to have had prior hospitalizations because of opportunistic infections, tended to be older and predominantly contracted HIV through heterosexual transmission. In contrast, those entering TTRA experienced quicker virologic suppression and superior immunologic recovery.