Acta ophthalmologica · 2025
Pregnancy as a risk factor for central serous chorioretinopathy: A systematic review and meta-analysis.
СтатьяСистематический обзорМетаанализНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Eriksen Nathalie Skovgaard, Fakhril-Din Zainab, Fasana Riccardo, Anguita Rodrigo, van Dijk Elon H C, Ferro Desideri Lorenzo, Grauslund Jakob, Stormly Hansen Michael, Klefter Oliver Niels, Motaabbed Armin, Petersen Line, Ramtohul Prithvi, Sabaner Mehmet Cem, Savran Osman, Schneider Miklos, Subhi Yousif
Аннотация
PURPOSE: Pregnancy induces significant changes in the body, including increased peripheral and choroidal blood perfusion and an increased systemic corticosteroid level. Here, we systematically reviewed the evidence on pregnancy as a risk factor for developing central serous chorioretinopathy (CSC) and conducted a meta-analysis to obtain a summary estimate.
METHODS: We searched 12 literature databases on 16 February 2025 for epidemiological studies, which evaluated the potential association between pregnancy and CSC. All eligible studies were included for a qualitative review and a meta-analysis. The meta-analysis was made using the random-effects model on the odds ratio (OR) of the association between pregnancy and CSC.
RESULTS: Four studies were eligible for our review. Of the 2766 individuals (1345 patients with CSC, 1391 controls) in these studies, females constituted 26%-64% of study populations in individual studies. The calculated summary estimate of pregnancy as a risk factor for CSC was OR 5.51 (95% CI: 2.12-14.30, p = 0.00046). Heterogeneity statistics suggested minimal to no heterogeneity (Cochran's Q = 0.72; I2 = 0%), the funnel plot was symmetrical and the sensitivity analysis suggested robustness of the estimates.
CONCLUSION: Pregnancy appears to be a significant risk factor for CSC.
METHODS: We searched 12 literature databases on 16 February 2025 for epidemiological studies, which evaluated the potential association between pregnancy and CSC. All eligible studies were included for a qualitative review and a meta-analysis. The meta-analysis was made using the random-effects model on the odds ratio (OR) of the association between pregnancy and CSC.
RESULTS: Four studies were eligible for our review. Of the 2766 individuals (1345 patients with CSC, 1391 controls) in these studies, females constituted 26%-64% of study populations in individual studies. The calculated summary estimate of pregnancy as a risk factor for CSC was OR 5.51 (95% CI: 2.12-14.30, p = 0.00046). Heterogeneity statistics suggested minimal to no heterogeneity (Cochran's Q = 0.72; I2 = 0%), the funnel plot was symmetrical and the sensitivity analysis suggested robustness of the estimates.
CONCLUSION: Pregnancy appears to be a significant risk factor for CSC.