Medicine and science in sports and exercise · 2026
The Effects of Time-Restricted Feeding and Exercise on Cardiometabolic Health in Sedentary Older Adults: A Randomized Controlled Trial.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Peng Linyu, Chen Lidan, Xia Jingbo, Zhou Jie, Shi Niujin, Cheng Ran, Shu Linjie, Huang Junhao, Hu Min, Liao Jingwen
Аннотация
PURPOSE: Exploring preferable lifestyle habits (diet and/or exercise) is essential in improving cardiometabolic health among older adults, who represent the most sedentary than other age populations and generally suffer from cardiometabolic problems. This study aimed to determine the effects of long-term time-restricted feeding (TRF), exercise training, and their combination on comprehensive measures of cardiovascular functions and multiple auxiliary indicators, and to simultaneously evaluate side effects and adherence.
METHODS: Fifty-six sedentary participants (age: 57.6 ± 2.2) were randomly assigned to control (CON; n = 14), exercise (EX; n = 14), TRF (n = 14), and a combinational intervention (EX+TRF; n = 14) group. Participants in each group were instructed to follow their assigned TRF and/or exercise protocol throughout an 8-wk period. The primary outcomes were changes in cardiovascular functions. Secondary outcomes included changes in body composition, metabolic parameters, circulating biomarkers, eating habits, and nutrient intake.
RESULTS: After 8 wks, EX (n = 11), TRF (n = 11), and EX+TRF (n = 14) produced significant increase in heart rate variability compared with CON (n = 11) ( P < 0.05); EX and EX+TRF also significantly improved flow-mediated dilation ( P < 0.05). TRF and EX+TRF significantly induced reductions in body fat percentage, lean mass, and total calorie consumption compared with CON ( P < 0.05); EX even induced significant increases in inflammatory biomarkers ( P < 0.05). Three interventions potentially caused adverse events but with no obvious difference; neither TRF nor EX produced superior adherence than the other, but there was lower compliance when counseling them both.
CONCLUSIONS: Sedentary older adults could achieve cardiovascular health benefits by choosing either TRF or exercise lifestyle, with no obvious difference in adverse events and adherence.
METHODS: Fifty-six sedentary participants (age: 57.6 ± 2.2) were randomly assigned to control (CON; n = 14), exercise (EX; n = 14), TRF (n = 14), and a combinational intervention (EX+TRF; n = 14) group. Participants in each group were instructed to follow their assigned TRF and/or exercise protocol throughout an 8-wk period. The primary outcomes were changes in cardiovascular functions. Secondary outcomes included changes in body composition, metabolic parameters, circulating biomarkers, eating habits, and nutrient intake.
RESULTS: After 8 wks, EX (n = 11), TRF (n = 11), and EX+TRF (n = 14) produced significant increase in heart rate variability compared with CON (n = 11) ( P < 0.05); EX and EX+TRF also significantly improved flow-mediated dilation ( P < 0.05). TRF and EX+TRF significantly induced reductions in body fat percentage, lean mass, and total calorie consumption compared with CON ( P < 0.05); EX even induced significant increases in inflammatory biomarkers ( P < 0.05). Three interventions potentially caused adverse events but with no obvious difference; neither TRF nor EX produced superior adherence than the other, but there was lower compliance when counseling them both.
CONCLUSIONS: Sedentary older adults could achieve cardiovascular health benefits by choosing either TRF or exercise lifestyle, with no obvious difference in adverse events and adherence.