Endovasal granulomatous lymphangiitis as a pathogenetic factor in cheilitis granulomatosa.

In 12 patients with cheilitis granulomatosa (ChG) epithelioid granulomas were histologically observed mostly within lympatic vessels. These granulomas appear to obstruct lymphatic lumina thus causing lymphostasis, lymphatic dilatation and lymphatic edema. The lack of literature concerning intraluminal localization of granulomas in cheilitis granulomatosa prompted the reporting of our observations.