[Naproxen-induced bullous photodermatitis (pseudoporphyria)].

The author describes two cases of naproxene-induced bullous photodermatitis (pseudoporphyria) with recurrent blisters and fragility of the skin of hands and face. The cutaneous changes were clinically and histologically indistinguishable from those noted in porphyria cutanea tarda, but were without the associated haematological abnormalities. The lesions remitted upon the cessation of naproxene therapy. Pseudoporphyria may be considered as a phototoxic reaction to drugs or unknown chromophores and is also seen in hemodialysis patients and users of UVA-sunbeds. Naproxene-induced pseudoporphyria has not been previously reported in Norway.