Journal of neuro-oncology · 2005
Assessment of neurolymphomatosis by brachial plexus biopsy and PET/CT. Report of a case.
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Bokstein Felix, Goor Odelyia, Shihman Boris, Rochkind Shimon, Even-Sapir Einat, Metser Ur, Neufeld Miri
Аннотация
OBJECTIVE: To report a biopsy-proven neurolymphomatosis in a young woman with previous non-Hodgkin's lymphoma (NHL) of uterine cervix.
PATIENT: The patient presented with a painful brachial plexopathy and developed multiple cranial and spinal nerve palsies.
METHODS AND RESULTS: The diagnosis was achieved by an open brachial plexus biopsy. A PET/CT study was used to assess the full extent of the disease and showed involvement of additional cranial nerves and spinal nerve roots. A complete although short lasting clinical and radiological response was achieved by means of systemic high dose methotrexate treatment combined with rituximab and intra-CSF injections of cytarabine.
PATIENT: The patient presented with a painful brachial plexopathy and developed multiple cranial and spinal nerve palsies.
METHODS AND RESULTS: The diagnosis was achieved by an open brachial plexus biopsy. A PET/CT study was used to assess the full extent of the disease and showed involvement of additional cranial nerves and spinal nerve roots. A complete although short lasting clinical and radiological response was achieved by means of systemic high dose methotrexate treatment combined with rituximab and intra-CSF injections of cytarabine.