Malaria journal · 2026
Cerebral malaria caused by Plasmodium vivax in an afrodescendant adult in Colombia: case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Sastre-Martínez Andrés David, Gutiérrez Michael Andres García, Vallejo-Serna Raúl Andrés, Muñoz-Lombo Jenny Patricia
Аннотация
BACKGROUND: Malaria, caused by parasites of the Plasmodium genus and transmitted by Anopheles mosquitoes, remains a global public health issue, with a high incidence in tropical and subtropical regions. Although Plasmodium falciparum is the main cause of severe cases, Plasmodium vivax can also lead to serious complications, including cerebral malaria.
CASE PRESENTATION: This case report presents the case of a 43-year-old woman from the southwestern Pacific coast, Colombia, who developed severe neurological symptoms with an initially unclear diagnosis. A thick blood smear confirmed P. vivax infection. She was treated with intravenous artesunate and subsequently with chloroquine and primaquine, and she achieved a full recovery.
CONCLUSIONS: Cerebral malaria has traditionally been associated with P. falciparum, P. vivax can also cause it through mechanical and inflammatory mechanisms, with a complex pathophysiology and potentially fatal outcomes. Early treatment with parenteral artesunate and intensive supportive care is key to improving outcomes.
CASE PRESENTATION: This case report presents the case of a 43-year-old woman from the southwestern Pacific coast, Colombia, who developed severe neurological symptoms with an initially unclear diagnosis. A thick blood smear confirmed P. vivax infection. She was treated with intravenous artesunate and subsequently with chloroquine and primaquine, and she achieved a full recovery.
CONCLUSIONS: Cerebral malaria has traditionally been associated with P. falciparum, P. vivax can also cause it through mechanical and inflammatory mechanisms, with a complex pathophysiology and potentially fatal outcomes. Early treatment with parenteral artesunate and intensive supportive care is key to improving outcomes.