Gan to kagaku ryoho. Cancer & chemotherapy · 2021
[Disseminated Bone Marrow Carcinomatosis from Colon Cancer-A Case Report].
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Ito Yoshiro, Shingai Tatsushi, Okimura Shumpei, Taniguchi Yoshiki, Fukata Tadafumi, Nishida Hisashi, Toyoda Yasuhiro, Takayama Osamu, Yoshioka Setsuko, Hojo Shigeyuki, Fukuzaki Takayuki, Ohigashi Hiroaki
Аннотация
A 77‒year‒old man came to our hospital with complaints of abdominal pain and difficulty to defecate. Abdominal CT scan showed an abnormal region in the ascending colon, which was suspected to be an ascending colon cancer. D‒dimer was remarkably high, and the platelet count was 63,000/μL; these results suggested disseminated intravascular coagulation caused by tumor activation. After he was admitted, we performed a contrast enhanced CT, and found no signs of remote metastasis. We decided to resect the tumor without colonoscopy examination in order to release the DIC state. After the surgery, the platelet count did not increase, and leukopenia was observed. We conducted a bone marrow biopsy, and made a diagnosis of disseminated carcinomatosis from colon cancer. The patient's condition did not improve, and he died on day 42 after admission. Pathological autopsy was performed and several minimal remote metastases were found throughout the body.