International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026
Analysis of clinical, imaging, and pathological features of osseous echinococcosis.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yimingjiang Maiweilidan, Pang Xuelian, Shi Yi, Ma Zhiping, Cui Wenli, Ma Wenmei
Аннотация
OBJECTIVE: To investigate the clinical, imaging, and pathological features of osseous cystic echinococcosis (CE) and osseous alveolar echinococcosis (AE) to enhance diagnostic accuracy and differential diagnosis capabilities.
METHODS: A retrospective analysis of 58 pathologically confirmed osseous echinococcosis cases was conducted, collecting demographic, clinical, imaging, and histopathological data.
RESULTS: Of 58 patients, 49 (84.5%) had osseous CE and 9 (15.5%) had osseous AE. Both types predominantly affected farmers/herdsmen. The spine was the most commonly affected site (CE: 70.4%, AE:44.4%), and multi-site involvement was common (CE: 71.4%, AE: 88.9%). Osseous CE showed multilocular cystic hypodense lesions (58.0%) on CT and ``grape-cluster-like'' lesions with long T1/T2 signals (90.2%), with ring-like enhancement of the cyst wall and septa sometimes on MRI. Osseous AE presented heterogeneous density with calcifications (50.0%) on CT, and MRI showed mixed signals, with calcifications and fibrous components showing low signals on T2WI. Histopathologically, osseous CE specimens contained "laminated membrane"-like material (68.4%); powder-stained plate-like stratum corneum was observed under the microscope (100%). Osseous AE displayed necrotic debris (70.0%); honeycomb-like microcysts were seen within the necrotic background (100%).
CONCLUSION: Osseous CE and AE share overlapping Clinical features, but exhibit differences in CT/MRI and pathological characteristics. Compared to osseous CE, osseous AE demonstrated broader site distribution, more frequent multisystem involvement, and a more aggressive clinical course with shorter disease duration prior to diagnosis. Mastering the key features is essential for accurate diagnosis.
METHODS: A retrospective analysis of 58 pathologically confirmed osseous echinococcosis cases was conducted, collecting demographic, clinical, imaging, and histopathological data.
RESULTS: Of 58 patients, 49 (84.5%) had osseous CE and 9 (15.5%) had osseous AE. Both types predominantly affected farmers/herdsmen. The spine was the most commonly affected site (CE: 70.4%, AE:44.4%), and multi-site involvement was common (CE: 71.4%, AE: 88.9%). Osseous CE showed multilocular cystic hypodense lesions (58.0%) on CT and ``grape-cluster-like'' lesions with long T1/T2 signals (90.2%), with ring-like enhancement of the cyst wall and septa sometimes on MRI. Osseous AE presented heterogeneous density with calcifications (50.0%) on CT, and MRI showed mixed signals, with calcifications and fibrous components showing low signals on T2WI. Histopathologically, osseous CE specimens contained "laminated membrane"-like material (68.4%); powder-stained plate-like stratum corneum was observed under the microscope (100%). Osseous AE displayed necrotic debris (70.0%); honeycomb-like microcysts were seen within the necrotic background (100%).
CONCLUSION: Osseous CE and AE share overlapping Clinical features, but exhibit differences in CT/MRI and pathological characteristics. Compared to osseous CE, osseous AE demonstrated broader site distribution, more frequent multisystem involvement, and a more aggressive clinical course with shorter disease duration prior to diagnosis. Mastering the key features is essential for accurate diagnosis.