Frontiers in pharmacology · 2026
An ethnopharmacological assessment of medicinal plants in Malanje Municipality, Angola.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Barroso Agostinho António, Martins André Alberto, Morais Agostinho, Katenda Peterson Carlos Foguete, Jamba Madalena Feca, Gonçalves Mateus Ferreira Alfredo, Sebastião Mateus André, Chimbuco Bernardo Nicodemo, Hernández Yanelis Saucedo, Mota Dany Siverio, Ribalta Venancio Ribalta, Gomes Amandio, Barreto Enoel Hernándes, Ekundi-Valentim Eduardo
Аннотация
BACKGROUND: Malanje Municipality in north-central Angola harbors exceptional botanical and cultural diversity, yet remains poorly documented for traditional medicinal plant knowledge; this study provides the first systematic ethnopharmacological baseline to guide pharmacological prioritization, conservation, and policy-relevant integration of traditional medicine.
METHODS: Between 2018 and 2023, we conducted semi-structured interviews (n = 20 traditional healers), participatory observation, in situ photographic documentation, and GPS mapping. Voucher specimens were taxonomically verified against herbarium material and online resources. Quantitative indices included frequency measures and rank order priority (ROP); therapeutic indications were grouped using ICD-11 categories.
RESULTS: Informants reported 272 ethnospecies, of which 78 taxa (39 families) were identified to species level. Fabaceae (9%), Asteraceae (6.4%), and Euphorbiaceae, Poaceae, and Zingiberaceae (each 5.1%) were most represented families. Leaves (53.8%) and roots (42.3%) were the principal parts used; decoction (60%) and maceration (31%) were the most common preparations. ROP prioritized Terminalia brachystemma (81.8), Securidaca longepedunculata (54.4), and Mondia whitei (52.2) for follow-up study. Treated conditions clustered in gastrointestinal disorders (43.6%) and infectious/parasitic diseases (29.5%). Healers reported several contraindications and observable adverse effects.
CONCLUSION: This work provides the first comprehensive ethnopharmacological register for Malanje Municipality, highlighting high-priority species for phytochemical, pharmacological, and toxicological evaluation and identifying conservation and sustainable-use concerns (notably root harvest). Limitations include a modest sample of informants and incomplete taxonomic resolution for many ethnospecies.
RECOMMENDATIONS: Expand sampling across the province, complete voucher identification, perform contamination and toxicity screening, and develop community-led cultivation and stewardship plans that align with Angola's National Policy for Traditional and Complementary Medicine.
METHODS: Between 2018 and 2023, we conducted semi-structured interviews (n = 20 traditional healers), participatory observation, in situ photographic documentation, and GPS mapping. Voucher specimens were taxonomically verified against herbarium material and online resources. Quantitative indices included frequency measures and rank order priority (ROP); therapeutic indications were grouped using ICD-11 categories.
RESULTS: Informants reported 272 ethnospecies, of which 78 taxa (39 families) were identified to species level. Fabaceae (9%), Asteraceae (6.4%), and Euphorbiaceae, Poaceae, and Zingiberaceae (each 5.1%) were most represented families. Leaves (53.8%) and roots (42.3%) were the principal parts used; decoction (60%) and maceration (31%) were the most common preparations. ROP prioritized Terminalia brachystemma (81.8), Securidaca longepedunculata (54.4), and Mondia whitei (52.2) for follow-up study. Treated conditions clustered in gastrointestinal disorders (43.6%) and infectious/parasitic diseases (29.5%). Healers reported several contraindications and observable adverse effects.
CONCLUSION: This work provides the first comprehensive ethnopharmacological register for Malanje Municipality, highlighting high-priority species for phytochemical, pharmacological, and toxicological evaluation and identifying conservation and sustainable-use concerns (notably root harvest). Limitations include a modest sample of informants and incomplete taxonomic resolution for many ethnospecies.
RECOMMENDATIONS: Expand sampling across the province, complete voucher identification, perform contamination and toxicity screening, and develop community-led cultivation and stewardship plans that align with Angola's National Policy for Traditional and Complementary Medicine.