[PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology].

INTRODUCTION

Photodynamic therapy (PDT) combines the use of a topical sensitizer and its excitation with a light of appropriate wavelength. Its use in dermatooncology has been possible in France in 2006 when the methyl ester ALA or Metvixia® got approved.

OBJECTIVE

To provide a panoramic view of validated indications of PDT in oncodermatology.

METHOD: This work is based on the review of the literature as well as available guidelines or recommendation on PDT in dermatology.

RESULTS

Standardized protocols and results of the main clinical trials are given for the three major indications in dermatology: actinic keratosis, basal cell carcinoma and Bowen disease.

CONCLUSION

PDT has its role to play in the treatment of multiple superficial carcinomas and cutaneous precancerous lesions and its main advantage resides in its optimal healing.