American journal of ophthalmology · 2003
Punctal-canalicular stenosis associated with mitomycin-C for corneal epithelial dysplasia.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Billing Kathryn, Karagiannis Arthur, Selva Dinesh
Аннотация
PURPOSE: To report a case of punctal-canalicular stenosis after topical mitomycin C use for corneal dysplasia. To the authors' knowledge, this association has not previously been described.
DESIGN: Observational case report.
METHOD: A 62-year-old woman was noted to have a right inferotemporal corneal dysplastic lesion. She received a topical course of mitomycin-C 0.04% four times a day, which subsequently invoked a toxoallergic reaction. One month later, the patient developed right-sided epiphora.
RESULTS: Probing demonstrated complete stenosis of the right lower canaliculus, 5 mm from the punctum.
CONCLUSION: Mitomycin-C use may lead to lacrimal apparatus fibrosis and symptomatic epiphora when inciting a toxoallergic reaction.
DESIGN: Observational case report.
METHOD: A 62-year-old woman was noted to have a right inferotemporal corneal dysplastic lesion. She received a topical course of mitomycin-C 0.04% four times a day, which subsequently invoked a toxoallergic reaction. One month later, the patient developed right-sided epiphora.
RESULTS: Probing demonstrated complete stenosis of the right lower canaliculus, 5 mm from the punctum.
CONCLUSION: Mitomycin-C use may lead to lacrimal apparatus fibrosis and symptomatic epiphora when inciting a toxoallergic reaction.