Infection · 2020
COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients.
СтатьяНазвание и аннотация: Перевод в очереди
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Härter Georg, Spinner Christoph D, Roider Julia, Bickel Markus, Krznaric Ivanka, Grunwald Stephan, Schabaz Farhad, Gillor Daniel, Postel Nils, Mueller Matthias C, Müller Markus, Römer Katja, Schewe Knud, Hoffmann Christian
Аннотация
INTRODUCTION: Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population.
METHODS: Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome.
RESULTS: Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir.
CONCLUSIONS: This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.
METHODS: Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome.
RESULTS: Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir.
CONCLUSIONS: This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.