Acta oto-laryngologica · 2026
Primary squamous cell carcinoma of the external auditory canal - a nationwide study.
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Sandström K, Olaison S, Werner M, Bonnard Å, Lindqvist O, Johansen A, Tulinius A, Krounis C, Eriksson P O
Аннотация
BACKGROUND: National studies on primary malignant tumours arising from the external auditory canal (EAC) are rare.
OBJECTIVES: To investigate the incidence and outcomes of squamous cell carcinoma of the external auditory canal (SCC-EAC) in Sweden.
MATERIALS AND METHODS: The retrospective study included patients diagnosed with SCC-EAC in Sweden from 2007 to 2017.
RESULTS: Forty-six patients with SCC-EAC were identified. The crude annual incidence was 0.043 per 100,000 inhabitants (age-standardised rate (ASR): 0.024 WHO, 0.045 Europe). Among the 40 patients treated with curative intent, 85% achieved remission, and 23% subsequently relapsed. Uncertain or non-radical primary surgery significantly correlated with residual tumour or relapse (p = 0.01) and disease-specific mortality (p = 0.002). Clear margins were achieved in 60% of T1 tumours and 21% of T4 tumours, indicating surgical undertreatment. None of the patients who underwent radical surgery died of SCC-EAC.
CONCLUSIONS AND SIGNIFICANCE: The incidence of SCC-EAC in Sweden was lower than international rates. Non-radical surgery drastically increased mortality, and postoperative radiotherapy (PORT) could not fully compensate for incomplete resection. Consequently, a more aggressive surgical approach is justified.
OBJECTIVES: To investigate the incidence and outcomes of squamous cell carcinoma of the external auditory canal (SCC-EAC) in Sweden.
MATERIALS AND METHODS: The retrospective study included patients diagnosed with SCC-EAC in Sweden from 2007 to 2017.
RESULTS: Forty-six patients with SCC-EAC were identified. The crude annual incidence was 0.043 per 100,000 inhabitants (age-standardised rate (ASR): 0.024 WHO, 0.045 Europe). Among the 40 patients treated with curative intent, 85% achieved remission, and 23% subsequently relapsed. Uncertain or non-radical primary surgery significantly correlated with residual tumour or relapse (p = 0.01) and disease-specific mortality (p = 0.002). Clear margins were achieved in 60% of T1 tumours and 21% of T4 tumours, indicating surgical undertreatment. None of the patients who underwent radical surgery died of SCC-EAC.
CONCLUSIONS AND SIGNIFICANCE: The incidence of SCC-EAC in Sweden was lower than international rates. Non-radical surgery drastically increased mortality, and postoperative radiotherapy (PORT) could not fully compensate for incomplete resection. Consequently, a more aggressive surgical approach is justified.