[Efficacy and safety of conservative and nasal endoscopic therapy for residual nasopharyngeal carcinoma].

Objective

To compare the efficacy and safety of conservative and nasal endoscopic therapy for residual nasopharyngeal carcinoma. Method:Eighty-two cases of residual nasopharyngeal carcinoma patients in our hospital were selected and according to the order of admission were equally divided into the nasal endoscopy group and the conservative group with 41 cases in each, the conservative group were given conservative treatment of radiotherapy and the nasal endoscopy group were given nasal endoscopic surgery, the effects , prognosis and complications were observed in the two groups. Result:The effective rates of nasal endoscopic group and conservative group were 92.7% and 75.6% after treatment for 6 moths, and the effective rate of nasal endoscopic group was significantly higher than that in conservative group (P<0.05). There were no serious complications such as massive hemorrhage of nose and throat and major organ damage in the two groups, and other complications were improved after symptomatic treatment. The overall survival, local recurrence free survival time and distant metastasis free survival time in the nasal endoscopic group were (34.24±2.19) months, (28.45±1.98) months and (26.33±2.88) months, were significantly higher than those of the conservative group (26.46±1.98)months, (21.87±2.09) months and (20.44±3.19) months(P<0.05).

Conclusion

Compares with conservative radiotherapy, nasal endoscopic surgery in the treatment of residual nasopharyngeal carcinoma can improve the efficacy and safety, so as to prolong the survival time of patients that has good application values.