Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024
[Chinese expert consensus on minimal residual disease detection in multiple myeloma based on bone marrow samples (2024)].
Consensus StatementАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Experimental Diagnostic Group, Plasma Cell Disease Group, Chinese Society of Hematology, Chinese Medical Association, Multiple Myeloma Professional Committee of Chinese Medical Doctor Association
Аннотация
Multiple myeloma (MM) is the second most common hematologic malignant tumor. Standard holistic treatment model and new drug-based regimens have greatly improved the survival of patients with MM; however, minimal residual disease (MRD) causes relapse in most patients. Therefore, combining MRD testing on the basis of traditional serological efficacy evaluation is necessary to achieve a more accurate assessment of the patient's disease status. At present, next-generation flow cytometry (NGF) and next-generation sequencing (NGS) are the mainstream technologies for detecting MRD based on bone marrow samples. To standardize and normalize MRD detection, the expert group discussed and formulated Chinese expert consensus on the application of NGF and NGS technology for bone marrow MRD detection in patients with MM.