Annals of maxillofacial surgery · 2023
Oral Manifestations of Malignant Immunoglobinopathy Hidden in Plain Sight - A Rare Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Sharma Naresh Kumar, Singh Akhilesh Kumar, Hirani Mehul Shashikant, Krishnan Aswathi, Mahajan Arjun, Rajpoot Ravina
Аннотация
RATIONALE: Radiolucent lesions over the angle-body region of the mandible are frequently difficult to diagnose but crucial to provide patient-centred care.
PATIENT CONCERNS: An elderly female presented with a painless slow-growing swelling over her left lower face for one year, radiographically appearing as a well-defined unilocular radiolucency over the left body of the mandible.
DIAGNOSIS: Aspiration was negative, and biopsy was inconclusive. Further imaging, bone marrow biopsy, immune profile and serum electrophoresis confirmed the diagnosis of multiple myeloma.
TREATMENT: She was referred to Medical Oncology for chemotherapy of lenalidomide, bortezomib and dexamethasone regimen cycle that was repeated every 21 days.
OUTCOMES: There was no increase in swelling, and radiographically 'punched-out' lesions were reduced significantly.
TAKE-AWAY LESSONS: Maxillofacial clinicians should be attentive to the oral manifestations of underlying disease, have a high index of suspicion and start the treatment promptly to increase chances of a favourable outcome.
PATIENT CONCERNS: An elderly female presented with a painless slow-growing swelling over her left lower face for one year, radiographically appearing as a well-defined unilocular radiolucency over the left body of the mandible.
DIAGNOSIS: Aspiration was negative, and biopsy was inconclusive. Further imaging, bone marrow biopsy, immune profile and serum electrophoresis confirmed the diagnosis of multiple myeloma.
TREATMENT: She was referred to Medical Oncology for chemotherapy of lenalidomide, bortezomib and dexamethasone regimen cycle that was repeated every 21 days.
OUTCOMES: There was no increase in swelling, and radiographically 'punched-out' lesions were reduced significantly.
TAKE-AWAY LESSONS: Maxillofacial clinicians should be attentive to the oral manifestations of underlying disease, have a high index of suspicion and start the treatment promptly to increase chances of a favourable outcome.