Gan to kagaku ryoho. Cancer & chemotherapy · 2012
[A case of liver metastases from gastric cancer successfully treated with weekly paclitaxel chemotherapy].
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Okada Kazuyuki, Ebisui Chikara, Murakami Masahiro, Yanagisawa Tetsu, Okamura Shu, Murata Kohei, Yokouchi Hideoki, Tamai Masamitsu, Kinuta Masakatsu
Аннотация
A 63-year-old woman underwent distal gastrectomy for gastric cancer (P+, CY+, Stage IV) in February 2011. About 3 months after surgery, abdominal computed tomography(CT) examination revealed solitary liver metastasis. Systemic chemotherapy was started using a regimen of S-1/cisplatin(CDDP). After 2 courses, an adverse reaction of grade 3 neutropenia occurred, although liver metastasis regression was confirmed. Weekly paclitaxel (PTX)was selected as the second -line chemotherapy. After 3 courses, imaging indicated complete regression of the liver metastasis. No adverse events occurred following 5 courses of weekly PTX. No recurrence was noted at a post-surgical follow-up of 15 months. We experienced a case of liver metastasis that was successfully treated with S-1/CDDP and weekly PTX chemotherapy.