Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
A systematic review: management of radiation-induced moist desquamation.
СтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Raja Sneha, Kuppusamy Sujatha, Johnson Christian Gnanaraj, Jayram Jayasutha, Kondaveeti Satish Srinivas
Аннотация
BACKGROUND: Radiotherapy is a cornerstone in cancer treatment, but is frequently correlated with acute cutaneous toxicity, particularly in patients with head, neck, and breast cancers. This systematic review evaluates the efficacy of interventions for managing grade III moist desquamation among various cancer patients receiving radiotherapy.
MATERIALS AND METHODS: A total of 676 studies were screened, and 10 randomised controlled trials were analysed based on inclusion criteria.
RESULTS: Interventions such as Mepitel Film, boron-based gel, and 0.1% Mometasone Furoate demonstrated significant efficacy in reducing the incidence and severity of moist desquamation compared to standard creams or placebo. Hydroactive colloid gels and aloe vera showed promise in alleviating symptoms and improving treatment adherence. Betamethasone effectively reduced grade 2 dermatitis but limitedly impacted severe grade 3 reactions.
CONCLUSIONS: The findings highlight the importance of tailoring interventions to individual patient needs and emphasize the need for further studies to validate treatments, explore long-term outcomes, and improve patient quality of life during radiotherapy.
MATERIALS AND METHODS: A total of 676 studies were screened, and 10 randomised controlled trials were analysed based on inclusion criteria.
RESULTS: Interventions such as Mepitel Film, boron-based gel, and 0.1% Mometasone Furoate demonstrated significant efficacy in reducing the incidence and severity of moist desquamation compared to standard creams or placebo. Hydroactive colloid gels and aloe vera showed promise in alleviating symptoms and improving treatment adherence. Betamethasone effectively reduced grade 2 dermatitis but limitedly impacted severe grade 3 reactions.
CONCLUSIONS: The findings highlight the importance of tailoring interventions to individual patient needs and emphasize the need for further studies to validate treatments, explore long-term outcomes, and improve patient quality of life during radiotherapy.