Peak Intraocular Pressure Time during Water Drinking Test and Its Relationship with Glaucoma Severity.

PURPOSE: To investigate the association between the time of occurrence of intraocular pressure (IOP) peaks during the water-drinking test (WDT) and visual field damage in a cohort of primary open-angle glaucoma (POAG) patients.

METHODS

In this retrospective, cross-sectional study, 98 eyes from 49 consecutive POAG patients were followed in a referral clinical practice. The relationship between the time when IOP peaks occurred during the WDT and the visual field mean deviation (MD) assessed with 24-2 visual field was tested with mixed-effects models.

RESULTS

MD value was significantly associated with the time of IOP peak occurrence (P = 0.020) when adjusting for the number of medications, but not with the IOP peak values (P = 0.238).

CONCLUSION

The time of IOP peaks occurrence during the WDT was associated with glaucoma severity among treated POAG patients.