American journal of surgery · 2024
Demystifying delays: Factors associated with timely treatment of adrenocortical carcinoma.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Passman Jesse E, Gasior Julia A, Ginzberg Sara P, Amjad Wajid, Bader Amanda, Hwang Jasmine, Wachtel Heather
Аннотация
BACKGROUND: Delays in management of adrenocortical carcinoma (ACC) may lead to worse outcomes. We assessed for delays in ACC treatment according to sociodemographic factors.
METHODS: We performed a retrospective cohort study of patients treated for ACC (2010-2019) utilizing the National Cancer Database. Cox proportional hazards modeling was used to evaluate the associations between sociodemographic, geographic, and clinical factors and time to intervention from diagnosis.
RESULTS: Across 1399 subjects treated for ACC, the median time to treatment was 27 days (IQR 15-47). Non-Hispanic Black patients (HR 0.798, p = 0.033) and patients aged 40-64 years (HR 0.800, p = 0.008) were at greater risk of delays in care, whereas female patients (HR 1.169, p = 0.011) and those with metastatic disease (HR 1.176, p = 0.010) received more timely care.
CONCLUSIONS: Older age, male sex, and Black race were associated with delays in care for ACC though these delays did not translate to worsened overall survival.
METHODS: We performed a retrospective cohort study of patients treated for ACC (2010-2019) utilizing the National Cancer Database. Cox proportional hazards modeling was used to evaluate the associations between sociodemographic, geographic, and clinical factors and time to intervention from diagnosis.
RESULTS: Across 1399 subjects treated for ACC, the median time to treatment was 27 days (IQR 15-47). Non-Hispanic Black patients (HR 0.798, p = 0.033) and patients aged 40-64 years (HR 0.800, p = 0.008) were at greater risk of delays in care, whereas female patients (HR 1.169, p = 0.011) and those with metastatic disease (HR 1.176, p = 0.010) received more timely care.
CONCLUSIONS: Older age, male sex, and Black race were associated with delays in care for ACC though these delays did not translate to worsened overall survival.