Balloon-mounted versus self-expandable stent in failed neurothrombectomy: a post hoc analysis of the SAINT study.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Mohammaden Mahmoud H, Martins Pedro N, Aboul-Nour Hassan, Al-Bayati Alhamza R, Hassan Ameer E, Tekle Wondwossen, Fifi Johanna T, Majidi Shahram, Kuybu Okkes, Gross Bradley A, Lang Michael, Cortez Gustavo M, Hanel Ricardo A, Aghaebrahim Amin, Sauvageau Eric, Tarek Mohamed A, Farooqui Mudassir, Ortega-Gutierrez Santiago, Zevallos Cynthia B, Galecio-Castillo Milagros, Sheth Sunil A, Nahhas Michael, Salazar-Marioni Sergio, Nguyen Thanh N, Abdalkader Mohamad, Klein Piers, Hafeez Muhammad, Kan Peter, Tanweer Omar, Khaldi Ahmad, Li Hanzhou, Jumaa Mouhammad, Zaidi Syed F, Oliver Marion, Salem Mohamed M, Burkhardt Jan-Karl, Pukenas Bryan, Vigilante Nicholas, Penckofer Mary, Siegler James E, Peng Sophia, Alaraj Ali, Grossberg Jonathan A, Nogueira Raul, Haussen Diogo C
Аннотация
OBJECTIVE: To compare the procedural and clinical outcomes of balloon-mounted stents (BMS) with those of self-expandable stents (SES).
METHODS: Retrospective analysis of a prospectively collected database from the Stenting and Angioplasty in NeuroThrombectomy (SAINT) consortium. Patients were included if thrombectomy had failed and they then underwent rescue emergency stenting. Patients treated with SES or BMS were compared using inverse probability of treatment weighting. The primary outcome was the final reperfusion as measured by the modified Thrombolysis in Cerebral Infarction (mTICI) Scale. Safety measures included rates of symptomatic intracranial hemorrhage, procedural complications, and 90-day mortality.
RESULTS: A total of 328 patients were included. Baseline clinical and procedural characteristics were well balanced among both groups. The BMS group (n=127) had higher rates of successful reperfusion (94.5% vs 86.6%, aOR=4.23, 95% CI 1.57 to 11.37, P=0.004) and increased likelihood of higher degree of final reperfusion on the mTICI Scale (acOR=2.06, 95% CI 1.19 to 3.57, P=0.01) than the SES group (n=201). No difference in modified Rankin Scale shift (acOR=0.98, 95% CI 0.54 to 1.79, P=0.95), rates of mRS0-2 (26% vs 36%, aOR=0.93, 95% CI 0.46 to 1.88, P=0.83) and mRS0-3 (43% vs 50%, aOR=0.92, 95% CI 0.51 to 1.66, P=0.77) at 90 days were noted. Safety measures were comparable in both groups.
CONCLUSION: The present study demonstrates higher reperfusion rates with BMS than with SES in failed thrombectomy procedures that involved rescue stenting. No differences in hemorrhagic complications or clinical outcomes were noted. Further larger controlled studies are warranted.