Медицинская библиотека · Annals of the American Thoracic Society · 2026

Disease modification and progression in pre-chronic obstructive pulmonary disease: an official American Thoracic Society workshop report.

Putcha Nirupama, Bhatt Surya P, Bon Jessica, Christenson Stephanie A, Han MeiLan K, Krishnan Jerry A, Martinez Fernando J, Casaburi Richard, Crapo James D, Curtis Jeffrey L, Diette Gregory B, Dransfield Mark T, Eakin Michelle N, Kalhan Ravi, Mannino David M, Montes de Oca Maria, Musick Hugh, Rowe Steven M, Smith Benjamin M, Salvi Sundeep, Soler Xavier, Wedzicha Jadwiga A, Wright Jean A, Woodruff Prescott G, Wise Robert A, Chang Valerie, Miller Bruce E, Crim Courtney, Drummond M Bradley, American Thoracic Society Clinical Problems Assembly and the American Thoracic Society Drug/Device Discovery and Development Committee

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Аннотация

Chronic obstructive pulmonary disease (COPD) is a highly prevalent and burdensome disease that develops over decades. Treatments for COPD are most commonly prescribed in later stages of the disease, leaving missed opportunities to modify the course of disease at earlier stages. This workshop was conducted to promote progress in the design and conduct of clinical trials of treatments that modify progression to COPD. The aims of the workshop were to provide an operational definition of pre-COPD and to discuss the elements and design of potential clinical trials in pre-COPD. The key focus areas of this workshop included: (1) defining a study population for pre-COPD clinical trials; (2) endpoints in pre-COPD clinical trials; and (3) design considerations for pre-COPD clinical trials.

Для цитирования: Putcha Nirupama, Bhatt Surya P, Bon Jessica, Christenson Stephanie A, Han MeiLan K, Krishnan Jerry A, Martinez Fernando J, Casaburi Richard, Crapo James D, Curtis Jeffrey L, Diette Gregory B, Dransfield Mark T, Eakin Michelle N, Kalhan Ravi, Mannino David M, Montes de Oca Maria, Musick Hugh, Rowe Steven M, Smith Benjamin M, Salvi Sundeep, Soler Xavier, Wedzicha Jadwiga A, Wright Jean A, Woodruff Prescott G, Wise Robert A, Chang Valerie, Miller Bruce E, Crim Courtney, Drummond M Bradley, American Thoracic Society Clinical Problems Assembly and the American Thoracic Society Drug/Device Discovery and Development Committee. Disease modification and progression in pre-chronic obstructive pulmonary disease: an official American Thoracic Society workshop report.. Annals of the American Thoracic Society. 2026. DOI: 10.1093/annalsats/aaoag034.

Предметные рубрики MeSH

Humans Pulmonary Disease, Chronic Obstructive Disease Progression United States Clinical Trials as Topic Societies, Medical

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