European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2026
Fate of the Aortic Root After Reconstruction With Felt Neomedia for Acute Type A Aortic Dissection.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Gillinov Lauren A, Kapoor Sankrit R, Sperry Alexandra E, Lao James, Bazianos Daniel, Goel Nicholas J, Berezowski Mikolaj, Brown Chase R, Lawrence Kendall M, Szeto Wilson Y, Desai Nimesh D
Аннотация
OBJECTIVES: We sought to characterize the durability of aortic root reconstruction with felt neomedia for acute type A aortic dissection (ATAAD).
METHODS: Of 894 patients undergoing type A aortic dissection repair between 2010 and 2024 at a single institution, 537 underwent aortic root reconstruction with felt neomedia and aortic valve resuspension (median age 64 years, 37.2% female). Median follow-up was 4.3 years. Outcomes included survival, proximal aortic reintervention, greater than moderate aortic insufficiency, and root dilatation. Predictors of a composite outcome-defined as proximal aortic reintervention, greater than moderate aortic insufficiency, or root dilatation ≥ 50 mm-were evaluated.
RESULTS: Preoperatively, 19.9% of patients had greater than moderate aortic insufficiency, and median root diameter was 39.0 mm. Thirty-day mortality was 12.8%, and 10-year survival was 52.3%. The cumulative incidence of proximal aortic reintervention at 1, 5, and 10 years was 0.4%, 2.4%, and 5.5%. During follow-up, 13 patients developed greater than moderate aortic insufficiency and 16 developed root dilatation ≥ 50 mm. Freedom from the composite outcome was 98.8% at 1 year and 91.9% at 5 years. On multivariable analysis, preoperative aortic insufficiency and baseline root diameter ≥ 45 mm were independent predictors of the composite outcome.
CONCLUSIONS: Aortic root reconstruction with felt neomedia and aortic valve resuspension is a durable technique for ATAAD. Patients with preoperative aortic insufficiency or root dilatation are at increased risk for root-related events and warrant close surveillance.
METHODS: Of 894 patients undergoing type A aortic dissection repair between 2010 and 2024 at a single institution, 537 underwent aortic root reconstruction with felt neomedia and aortic valve resuspension (median age 64 years, 37.2% female). Median follow-up was 4.3 years. Outcomes included survival, proximal aortic reintervention, greater than moderate aortic insufficiency, and root dilatation. Predictors of a composite outcome-defined as proximal aortic reintervention, greater than moderate aortic insufficiency, or root dilatation ≥ 50 mm-were evaluated.
RESULTS: Preoperatively, 19.9% of patients had greater than moderate aortic insufficiency, and median root diameter was 39.0 mm. Thirty-day mortality was 12.8%, and 10-year survival was 52.3%. The cumulative incidence of proximal aortic reintervention at 1, 5, and 10 years was 0.4%, 2.4%, and 5.5%. During follow-up, 13 patients developed greater than moderate aortic insufficiency and 16 developed root dilatation ≥ 50 mm. Freedom from the composite outcome was 98.8% at 1 year and 91.9% at 5 years. On multivariable analysis, preoperative aortic insufficiency and baseline root diameter ≥ 45 mm were independent predictors of the composite outcome.
CONCLUSIONS: Aortic root reconstruction with felt neomedia and aortic valve resuspension is a durable technique for ATAAD. Patients with preoperative aortic insufficiency or root dilatation are at increased risk for root-related events and warrant close surveillance.